Integration of Metabolomic and Brain Imaging Data Highlights Pleiotropy Among Posttraumatic Stress Disorder, Glycoprotein Acetyls, and Pallidum Structure.

Biol Psychiatry Glob Open Sci · 2025 · PMC12013147 · PMID 40270839

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0.0320

closest p · 0.6× alpha

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boldest claim

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nominally significantp = .032actually significant

Similarly, leveraging a depression GWAS that includes up to 1,999,601 EUR individuals ( 26 ), depression showed only a nominally significant genetic correlation with GlycA ( r g = 0.138, SE = 0.064, p = .032), with an estimate that was about half of the one observed for PTSD.

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