Pak1 dysregulates pyruvate metabolism in PDAC cells by exerting a phosphorylation-mediated regulatory effect on PDHA1.

J Biol Chem · 2025 · PMC12013493 · PMID 40090587

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moderately significantno p-value reported

In the Pak1 stable rescue clone, the restoration of Pak1 expression in Pak1 KO cells led to a moderately significant decline in the PDHA1 activity, comparable with WT cells.

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