Psilocybin reduces heroin seeking behavior and modulates inflammatory gene expression in the nucleus accumbens and prefrontal cortex of male rats.

Mol Psychiatry · 2025 · PMC12015112 · PMID 39433903

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Rats infused with the IL-17a antibody into the PFC displayed a trend for reduced Fos activity in the PFC that did not reach statistical significance (Mann-Whitney test U = 12.50, p = 0.07; Fig. 6G ).

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