Optimal duration of anticoagulation after left atrial appendage closure: a systematic review and meta-analysis.

BMC Cardiovasc Disord · 2025 · PMC12016058 · PMID 40264015

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did not reach statistical significanceno p-value reported

Notably, in the HAS-BLED < 3 subgroup, the difference between the two groups did not reach statistical significance, probably because prolonged anticoagulation did not significantly increase the risk of bleeding in the low-bleeding-risk population.

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