Genetic risk for neurodegenerative conditions is linked to disease-specific microglial pathways.

PLoS Genet · 2025 · PMC12017514 · PMID 40202986

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nominally significantno p-value reported

A previous study using LDSC to assess genome-wide genetic correlations (rg) found a low correlation between neurodegenerative GWAS datasets, with nominally significant positive associations between AD-ALS (0.19), AD-PD (0.23), and PD-ALS (0.23) [ 70 ].

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