Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling.

Elife · 2025 · PMC12017770 · PMID 40266667

Europe PMC DOI

hedged sentence

0.0533

closest p · 1.1× alpha

0.0533

boldest claim

The sentences

did not reach statistical significancep=0.0533so close (0.05 < p ≤ 0.1)

Impairing FP receptor signaling with AL-8810 (10 μM, Table 3 , n=9 arterioles, Figure 5G and H ) tended to reduce the evoked vasoconstriction, however, it did not reach statistical significance (AUC = –1.9 ± 0.4 x 10 3 %.s, t (17) = 2.82, p=0.0533).

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