Barely Significant
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Claudin 18.2: a promising actionable target in biliary tract cancers.

ESMO Open · 2025 · PMC12018027 · PMID 40215597

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0.1060
closest p · 2.1× alpha
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boldest claim

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did not reach statistical significanceP = 0.106not close (p > 0.1)
Likewise, CLDN18 positivity was higher in large duct iCCAs than in small duct iCCAs, but this difference did not reach statistical significance [6.7% (2/30) versus 0.9% (1/117), P = 0.106].

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