Birch pollen allergen-induced dsDNA release activates cGAS-STING signaling and type 2 immune response in mice.

Amphiregulin (AREG), a critical component of type 2 mediated tissue repair, 11 was increased after BPE challenge, and less so in cGAS −/− mice, although this did not reach statistical significance, while it was not affected in STING −/− mice ( Figure 2 J).

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