Tumor-infiltrating lymphocytes as predictive biomarkers in neoadjuvant treatment of HER2-positive breast cancer.

Oncologist · 2025 · PMC12019226 · PMID 40271640

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.4700

boldest claim

The sentences

highly significantP < .01actually significant

The paired t -test analysis for the low TIL level group also revealed a highly significant reduction in Ki67 levels following treatment ( P < .01), indicating effective Ki67 suppression in patients with low TIL levels ( Supplementary Figure S2B ).

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did not reach statistical significanceP = .470not close (p > 0.1)

TIL ≥ 10, while indicative of an association with pCR in univariate analysis, did not reach statistical significance in the regression model ( P = .470, OR = 1.453).

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