NKG2D-CAR-targeted iPSC-derived MSCs efficiently target solid tumors expressing NKG2D ligand.

24 , 25 , 26 , 27 However, we also noted a significant upregulation of the T cell activation marker CD69 in both B6-iMSCs and NKG2D-CAR-iMSCs ( Figure 6 F), which was consistent with our previous findings, 28 as well as a modest increase in the proliferation marker Ki67, although the latter did not reach statistical significance ( Figure 6 G).

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