Rare MTNR1B variants causing diminished MT2 signalling associate with elevated HbA<sub>1c</sub> levels but not with type 2 diabetes.

Diabetologia · 2025 · PMC12021717 · PMID 40064676

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nominally significantno p-value reported

However, carriers of variants impairing MT2 signalling demonstrated a nominally significant lower glucose-stimulated insulin response (β −0.47 SD [95% CI −0.82, −0.11]).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Rare MTNR1B variants causing diminished MT2 signalling associate with elevated HbA&lt;sub&gt;1c&lt;/sub&gt; levels but not with type 2 diabetes.

The sentences

Rare MTNR1B variants causing diminished MT2 signalling associate with elevated HbA<sub>1c</sub> levels but not with type 2 diabetes.