Continuous collection of human mesenchymal-stromal-cell-derived extracellular vesicles from a stirred tank reactor operated under xenogeneic-free conditions for therapeutic applications.

Although the difference did not reach statistical significance, the relative EV internalization appeared higher for HUVECs compared to the breast cancer cell lines (bottom panel, Fig. 5 D), suggesting a potential increased affinity for MSC-EV uptake.

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