Although this result was not statistically significant, the p -value approached the conventional threshold, indicating a possible trend toward increased risk.
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Effect of re-excision on local recurrence in patients with involved or close margins after upfront breast-conserving surgery: a systematic review and meta-analysis.
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The sentences
A trend toward an increased risk of local recurrence was observed in patients with carcinoma in situ who underwent re-excision; however, this finding did not reach statistical significance.