The Clinical Relevance of Epithelial-to-Mesenchymal Transition Hallmarks: A Cut-Off-Based Approach in Healthy and Cancerous Cell Lines.

Not statistically significant but showing an increasing trend is also the level of the EMT-TF ZEB1 .

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On the contrary, MMP9 seemed completely nonspecific and not correlated to an increase in cancer cell aggressiveness, while other genes such as VIM , CDH5 , and MCAM showed a trend toward an increased expression in the metastatic counterpart, albeit not statistically significant.

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