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Effects of <i>Alnus japonica</i> Pilot Scale Hot Water Extracts on a Model of Dexamethasone-Induced Muscle Loss and Muscle Atrophy in C57BL/6 Mice.

Int J Mol Sci · 2025 · PMC12027306 · PMID 40332160

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showed a trendno p-value reported
AJHW also showed a trend of restoring antioxidant enzyme activity (SOD, Catalase, GPx), which may have contributed to the improvement of muscle atrophy.

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a decreasing trendno p-value reported
In the muscle atrophy test groups (G2, G3, G4, G5, G6), the expression of TNF-α mRNA was significantly decreased in the 100 mg/kg AJHW treatment group (G5) compared to the muscle atrophy control group (G2), and the expression of IL-1β and IL-6 mRNA showed a decreasing trend with the treatment, but the differences were not significant ( Figure 10 ). 2.9.3.

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