Barely Significant
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Increased Myocardial <i>MARK4</i> Expression in Patients with Heart Failure and Sleep-Disordered Breathing.

Int J Mol Sci · 2025 · PMC12027440 · PMID 40332117

2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0700
boldest claim

The sentences

highly significantp < 0.001actually significant
Linear regression analysis revealed a highly significant negative correlation between the LVEF and the MARK4 expression (β = −0.044, 95% confidence interval: −0.059 to −0.030, p < 0.001) ( Figure 2 C).

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a strong trendp = 0.070so close (0.05 < p ≤ 0.1)
In line with these findings, we observed a strong trend ( p = 0.070) toward increased N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) levels, which were more than doubled in patients with a higher MARK4 expression ( Table 1 ).

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