Cognitive and Neuropsychiatric Effects of 40 Hz tACS Simultaneously with Cognitive Exercises for Dementia: A Randomized, Crossover, Double-Blind, Sham-Controlled Study.

One study applying 40 Hz tACS over the left angular gyrus for 14 weeks showed a trend toward improvements at the end of the treatment period and toward sustained benefits lasting 2–3 months when measured using the Memory Index Score [ 10 ].

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Results showed that both groups revealed statistically significant improvements in WMS scores from baseline to post-treatment; however, only the tACS with cognitive training group showed a marginally significant trend towards sustained improvement at the 1-month follow-up.

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