Post-infusion EEGs abnormalities were associated to a significant higher risk of ICANS when scored 2 [HR 11.6; 95% CI 4.4–30.5] and 3 [HR 9.7; 95% CI 2.6–36.6], while grade 1 abnormalities showed a trend of higher risk [HR 3.2; 95%CI 0.7–14.9] (Table 2 ).
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EEG as a predictive biomarker of neurotoxicity in anti-CD19 CAR T-cell therapy.
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