Long-Term Efficacy and Potential Predictors of Tralokinumab Dose Optimization in Elderly Patients: A Multicentre Study.

Dermatol Ther (Heidelb) · 2025 · PMC12033154 · PMID 40232593

Europe PMC DOI

hedged sentences

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

approached significancep = 0.068so close (0.05 < p ≤ 0.1)

Male sex ( p = 0.042) and a higher baseline EASI score ( p = 0.004) were associated with higher EASI values at week 16, while the prurigo subtype of AD approached significance ( p = 0.068).

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a trend toward significanceno p-value reported

A shorter time to initiation of systemic therapy ( p = 0.023) was associated with a higher likelihood of dose optimization, while a lower BMI ( p = 0.099) showed a trend toward significance.

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