The guanine nucleotide exchange factor Ric-8A regulates the sensitivity of constitutively active Gαq to the inhibitor YM-254890.

J Biol Chem · 2025 · PMC12033907 · PMID 40118458

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

αqAG-QP YM-sensitivity was slightly and consistently decreased, but this did not reach statistical significance ( 39 , 40 ), highlighting that the proline and leucine mutations are not entirely identical.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.