The Barcelona baseline risk score to predict long-term prognosis after a first demyelinating event: a prospective observational study.

Association between DMT exposure and long-term outcomes When DMT exposure was considered as a time-varying covariate in the predictive models (see methods), it was associated with a lower risk of developing the event immediately afterwards, for all clinical outcomes—although for ‘some RAW’ and ‘yearly rate of new T2 lesions>2’ the association did not reach statistical significance ( Fig. 4 ).

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