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Immunologic changes in the peripheral blood transcriptome of individuals with early-stage chronic Chagas cardiomyopathy: a cross-sectional study.

Lancet Reg Health Am · 2025 · PMC12033964 · PMID 40290486

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Immune cell deconvolution also shows a trend toward a possible reduction in classical and non-classical monocytes (antigen presenting cells) in Chagas early-CCC compared to the indeterminate stage, though this finding did not reach statistical significance ( Fig. 3 b, Supplementary Figure S2 ).

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