Development of an adipocyte differentiation protocol using 3T3-L1 cells for the investigation of the browning process: identification of the PPAR-γ agonist rosiglitazone as a browning reference drug.

Front Pharmacol · 2025 · PMC12034677 · PMID 40297148

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a positive trendno p-value reported

Furthermore, the analysis of UCP-1 levels in the cell lysate highlights a positive trend in all the treatments.

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did not reach statistical significanceno p-value reported

UCP-1 levels analyzed after 10 days of differentiation in the presence of RGZ 0.1 μM showed a positive trend that did not reach statistical significance, highlighting a higher variability than the data obtained on the 16th day.

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