Dietary supplementation of male mice with inorganic, organic or nanoparticle selenium preparations: evidence supporting a putative gut-thyroid-male fertility axis.

Data from this study shows testicular GPX1/GPX4 concentration increased significantly in NaSe-, Met-, and NanoSe-groups vs the control (at least p ≤ 0.05); testicular SOD and CAT activities remained unchanged, with only a weak trend to increase in the NanoSe group.

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Total GPX4 from NaSe group and DOI1 levels from all Se-supplemented groups trended to increase, meanwhile mice fed DPDS showed a trend to lower GPX4 levels although none were significant ( Figure 11 (b, c)).

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