Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential.

Proc Natl Acad Sci U S A · 2025 · PMC12037037 · PMID 40228113

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hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

approached significanceP = 0.07so close (0.05 < p ≤ 0.1)

There was no statistical difference in the total number of trials completed, though the number of omission trials approached significance ( P = 0.07) when comparing stressed animals that received vehicle or (+)-JRT ( SI Appendix , Fig.

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