Effectiveness and safety of dupilumab in children with moderate-to-severe asthma in China: A retrospective real-world study.

Chin Med J (Engl) · 2025 · PMC12037085 · PMID 40097367

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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an increasing trendP <0.001actually significant

Following treatment with dupilumab, the patients in the 6–11-year-old cohort showed an increasing trend in c-ACT scores at each follow-up timepoint ( P <0.001) [Figure 1 D].

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a decreasing trendno p-value reported

Conversely, ACQ-7-IA scores demonstrated a decreasing trend at each follow-up timepoint [Figure 1 E].

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did not reach statistical significanceno p-value reported

In our study population, we observed an initial increase in blood eosinophils counts during the first 3 months of dupilumab treatment, although the difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.