Opposite sex housing enhances reproductive function and induces transcriptional changes in the preoptic area of GnRH-deficient mice.

Front Endocrinol (Lausanne) · 2025 · PMC12037384 · PMID 40303641

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Although two-way ANOVA failed to detect a significant effect of housing on GnRH peptide and transcript, OS-housed dnFGFR mice showed a trend towards increased GnRH expression compared to SS-housed counterparts ( Figure 3B ), suggesting enhanced GnRH neuronal activation in progress.

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