Treatment of Large Cartilage Defects in the Knee by Hydrogel-Based Autologous Chondrocyte Implantation: A 5-Year Follow-Up of a Prospective, Multicenter, Single-Arm Phase III Trial.

Other Clinical Efficacy Results The IKDC subjective score and the EQ-5D-5L (index value and VAS) showed highly consistent outcomes in line with the KOOS outcomes, i.e., early, increasing, and nominally significant improvements from (including) Month 3 onwards until Year 1 and sustained or even further slightly increasing improvements through Year 5 ( Table 3 ).

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