Stretch regulation of β2-Adrenoceptor signalling in cardiomyocytes requires caveolae.

Cardiovasc Res · 2025 · PMC12038227 · PMID 39945052

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an increasing trendno p-value reported

There is an increasing trend in sarcomere shortening even under normal osmotic pressure conditions.

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a slight trendno p-value reported

did not reach statistical significanceno p-value reported

We rather saw a slight trend towards a decrease in cAMP release in stretched Cav3KO trabeculae after both β 1 AR and β 2 AR stimulation, though this trend did not reach statistical significance.

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