Inappropriate dosing of direct oral anticoagulants among very older inpatients with atrial fibrillation.

Although there were fluctuations and the differences are not significant, it can be observed that the proportion of recommended dosing (51.2% in 2018 to 58.8% in 2023, p = 0.09) shows an increasing trend, while the proportions of underdosing (42.7% in 2018 to 39.5% in 2023, p = 0.19) and overdosing (6.1% in 2018 to 1.7% in 2023, p = 0.32) show a gradually decreasing trend.

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Although the proportion of recommended dosing increased over the study period, and inappropriate dosing showed a declining trend, these changes did not reach statistical significance.

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