Toxoplasmosis accelerates the progression of hereditary spastic paraplegia.

Although no changes reached statistical significance, HSP mutant rats exhibited an overall trend toward reduced activity with reduced mean speed and distance traveled, and increased time spent freezing in all three time periods ( Fig. 2B through D ; Fig.

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Although the difference in ventricle size between the HSP mutant and the wild-type animals did not reach statistical significance in the results presented here ( Fig.

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