Barely Significant
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Spatial mapping of the AA-PGE<sub>2</sub>-EP axis in multiple sclerosis lesions.

Acta Neuropathol · 2025 · PMC12041062 · PMID 40299057

Europe PMCDOI
2
hedged sentences
0.0580
closest p · 1.2× alpha
0.1360
boldest claim

The sentences

a positive trendp = 0.058so close (0.05 < p ≤ 0.1)
Microglial EP2 expression (MI) was higher in the lesion ( p = 0.029) and showed a positive trend in the peri-lesional tissue ( p = 0.058) compared to NNC (Fig. 4 e).

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a negative trendp = 0.136not close (p > 0.1)
None of the correlations reached significance (partial r s = − 0.143, p = 0.783; absent: r s = − 0.214, p = 0.662) and PGE 2 /AA ratios in full myelinated regions showed a negative trend with immune cell activation ( r s = − 0.714, p = 0.136).

also in 1,447 other papers

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