Superior survival in diffuse large B cell lymphoma of the bone with immune rich tumor microenvironment.

Blood Cancer J · 2025 · PMC12041202 · PMID 40301298

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0670

boldest claim

The sentences

highly significantp < 0.001actually significant

Comparison of the unsupervised clustering from the total cohort and the bone cohort, showed highly significant overlap ( p < 0.001).

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borderline significantp = 0.067so close (0.05 < p ≤ 0.1)

However, it was borderline significant when adjusted for the IPI score (age, LDH, Ann Arbor, WHO status), with a hazard ratio of 2.9 (95% confidence interval: 0.93–8.82, p = 0.067).

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did not reach statistical significanceno p-value reported

Although a survival difference was observed between the clusters within the bone-DLBCL cohort, it did not reach statistical significance, likely due to the limited number of events.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.