A multi-omic approach implicates novel protein dysregulation in post-traumatic stress disorder.

Genome Med · 2025 · PMC12042318 · PMID 40301990

Europe PMC DOI

hedged sentences

0.0170

closest p · 0.3× alpha

0.0170

boldest claim

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highly significantP -value = 0.017actually significant

We also identified one protein module (PTSD-PM- midnightblue ) with highly significant enrichment ( P -value = 0.017) for ALZ risk variants.

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nominally significantno p-value reported

Overall, top regulated DEPs for PTSD have significant or nominally significant changes in MDD, especially in DLPFC.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.