Xijiao Dihuang Decoction for Sepsis-Induced Acute Lung Injury: Network Pharmacology and Molecular Dynamics Insights.

J Inflamm Res · 2025 · PMC12042965 · PMID 40309305

Europe PMC DOI

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did not reach statistical significancep > 0.05actually significant

Notably, Bcl-2 expression significantly rose in the XJDH-H group ( p < 0.01), whereas in the XJDH-L group, this change did not reach statistical significance ( p > 0.05).

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a decreasing trendno p-value reported

Furthermore, compared to the XJDH-L group, the expression levels of Bax and Cleaved-Caspase-3 in the XJDH-H group showed a decreasing trend, suggesting that the effect of XJDHD on apoptosis-related proteins may be dose-dependent.

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