CCR9 shapes the immune microenvironment of colorectal cancer modulating the balance between intratumoral CD8+ T cell and FoxP3+ Helios+ Treg subpopulations.

PLoS One · 2025 · PMC12043142 · PMID 40305493

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0.0693

closest p · 1.4× alpha

0.0693

boldest claim

The sentences

showed a trendp=0.0693so close (0.05 < p ≤ 0.1)

CCR9 −/− mice showed a trend to develop less tumors than CCR9 +/− mice (p=0.0693) ( Fig 1E , F ) and developed significantly less tumors of 2–3 mm in size ( Fig 1F ), indicating that expression CCR9 may favor colon cancer development.

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