nominally significantp = 0.026
The lowest p -value was found for a negative age-by-A1 orth interaction effect on the nucleus accumbens (beta = −0.410, p = 0.004, p FDR = 0.017), followed by a trend positive correlation with A1 orth (beta=0.346, p = 0.015, p FDR = 0.058) and a nominally significant A1 orth -by-A2-association (beta = −0.082, p = 0.026, p FDR = 0.104) (Table 1 ).