However, a significant interaction was detected in the heart failure subgroup (p = 0.04), where patients with heart failure showed a trend toward reduced MACE risk with empagliflozin compared to dapagliflozin (RR: 0.90, 95% CI: 0.82 to 1.00, I2 = 19%), while no such trend was observed in patients without heart failure (RR: 1.02, 95% CI: 0.97 to 1.07, I2 = 9%).
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Comparative Cardiovascular Outcomes of Dapagliflozin Versus Empagliflozin in Patients With Type 2 Diabetes: A Meta-Analysis
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