Barely Significant
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Alterations in <i>HMGB1, ROS1, FGFR1, FGFR2, IL6</i>, and <i>TLR4</i> are associated with worse survival in patients with esophageal squamous cell carcinoma.

Contemp Oncol (Pozn) · 2025 · PMC12051876 · PMID 40330450

2
hedged sentences
0.0000
closest p · 0.0× alpha
0.0800
boldest claim

The sentences

highly significantp < 1E-10actually significant
The altered group had a significantly higher mutation count (median 158.5) compared with the unaltered group (median 56), with a highly significant difference ( p < 1E-10).

also in 132,142 other papers

did not reach statistical significancep = 0.080so close (0.05 < p ≤ 0.1)
ROS1 and FGFR1 had a log 2 odds ratio of 1.879, although the association did not reach statistical significance ( p = 0.080).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.