Optimal Medical Therapy for Heart Failure and Integrated Care in Patients With Atrial Fibrillation: A Report From the ESC-EHRA EORP Atrial Fibrillation Long-Term General Registry.

35 , 36 Moreover, a recent meta‐analysis showed that the combination of drugs used in our study to define OMT provided a strong trend for the reduction of all‐cause death and HF hospitalization. 37 Because our study aimed to reflect real‐world clinical practice, we believe that our results depict the usual clinical approach, even though this remains a limitation and our conclusions about OMT use in HFpEF and HFmrEF must be taken with caution.

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