Barely Significant
← all excerpts

Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables.

Hum Vaccin Immunother · 2025 · PMC12054927 · PMID 40189906

Europe PMCDOI
1
hedged sentence
0.0630
closest p · 1.3× alpha
0.0630
boldest claim

The sentences

showed a trendp = .063so close (0.05 < p ≤ 0.1)
However, a previous study in the Caucasian population (Spain) showed a trend between the FCER1B rs573790-CC genotype (OR = 4.26; 95%CI = 1.01–26.98; p = .063) and a better response in reducing exacerbations. 33 Another author also associated this genotype with asthma and aspirin-exacerbated respiratory disease in a mestizo population (Mexico). 34 The Fc region of IgG enhances drug stability and prolongs its half-life, improving its pharmacokinetics. 35 The Fc region of human IgG1 binds selectively to Fc-gamma receptors (FcγR) on the surface of B lymphocytes, dendritic cells (DCs), and macrophages.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.