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Real-world use of over-the-counter medications by patients with migraine in Japan: results from the OVERCOME (Japan) 2nd study.

J Headache Pain · 2025 · PMC12056991 · PMID 40335927

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showed a trendno p-value reported
In the MHD subgroups, an increase in the number of MHDs showed a trend of greater respondent burden and doctor visits.

also in 53,322 other papers

a notable trendno p-value reported
When the respondents were grouped by monthly days of OTC drug use, there was a notable trend: respondents with ≥ 10 monthly days of OTC drug use were diagnosed with migraine the earliest in life (mean age 25.1 years).

also in 2,380 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.