Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells.

J Transl Med · 2025 · PMC12063457 · PMID 40346550

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did not reach statistical significanceno p-value reported

The results of the present study showed that hypoxia upregulated EPAC1 mRNA in control hcSMCs (although this effect did not reach statistical significance), while it downregulated EPAC1 mRNA in foam hcSMCs.

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