Cellular immune signatures and differences of four porcine circovirus type 2 vaccines to heterologous PCV2d infection.

Although the secondary expansion of PCV2-ORF2-specific IFNγ-SCs was not evident post-challenge in this study, triple-cytokine co-producing T cells showed a trend of progressive increase from 0 dpc (28 dpv) to 14 dpc in both frequencies and responder numbers.

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