In the 26–52 weeks subgroup, eculizumab appeared to exhibit a higher risk of general infection (RR = 1.22; 95% CI: 0.96–1.55; I 2 = 0%), though this difference did not reach statistical significance ( Supplementary Figure S3 ).
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Incidence of infection associated with eculizumab: a meta-analysis of 9 randomized controlled trials.
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