Barely Significant
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Misfolded α-synuclein co-occurrence with Alzheimer's disease proteinopathy.

Alzheimers Dement · 2025 · PMC12069017 · PMID 40356020

1
hedged sentence
0.1000
closest p · 2.0× alpha
0.1000
boldest claim

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did not reach statistical significancep < 0.10so close (0.05 < p ≤ 0.1)
For Digit Symbol Substitution, only the linear age interaction was significant ( 4 way × age , p = 0.0073), and pairwise trend contrasts once more indicated differences between the synSAA–/AD– group and the synSAA–/AD+ and synSAA+/AD+ groups (Model 4C), although after adjustment for multiplicity these did not reach statistical significance (0.05 < p < 0.10).

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