Assessing the Noninferiority of the Spermidine Hyaluronate Complex Relative to 17β-Estradiol Treatment in the Ovariectomized Murine Model of Vulvovaginal Atrophy.

J Menopausal Med · 2025 · PMC12070118 · PMID 40347164

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showed a trendno p-value reported

Histological evaluation of epithelial and endometrial thickness When we measured the vaginal epithelial thickness it just showed a trend in amelioration in E2 and Spd-HA groups compare to HA alone without significant statistical differences.

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