reached borderline significanceP = 0.050
In multivariable analyses, the time period when the operation was performed reached borderline significance as an independent prognostic factor for DMFS in LPS ( P = 0.050) and was statistically significant when comparing TP1 versus TP3 (HR 3.21, P = 0.025) and TP2 versus TP3 (HR 2.87, P = 0.029) separately ( Table S3 ).