Association Between Vaginal Microbiota and Cervical Dysplasia Due to Persistent Human Papillomavirus Infection: A Systematic Review of Evidence from Shotgun Metagenomic Sequencing Studies.

Int J Mol Sci · 2025 · PMC12072622 · PMID 40362493

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a clear trendno p-value reported

However, a clear trend of increased anaerobe and decreased Lactobacillus enrichment is observed.

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highly significantno p-value reported

Lactobacillus genus has been found to be a highly significant biomarker for distinguishing tumor (CC or CIN) and non-tumor (HPV or healthy) patients, including the most influential biomarkers, L. iners , L. crispatus , and G. vaginalis [ 7 ]. 3.5.

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