Cardiopulmonary Exercise Testing Correlates with Quantitative Left Ventricular [<sup>99m</sup>Tc]-DPD Uptake in Transthyretin Amyloid Cardiomyopathy.

Although the difference was not statistically significant, a positive trend toward event-free survival was observed for the patients with better baseline peak VO 2 in Kaplan–Meier analysis [ p = 0.076, HR 0.384 (95% Confidence interval (CI):0.128–1.151), p = 0.088], as illustrated in Figure A1 .

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This limitation is particularly relevant when assessing the impact of high DPD uptake on survival, where the trend observed did not reach statistical significance.

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